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For other uses, see Stress.
Stress is the condition that results when person-environment transactions lead the individual to perceive a discrepancy, whether real or not, between the demands of a situation and the resources of the person\'s biological, psychological or social systems. In medical terms, stress is the disruption of homeostasis through physical or psychological stimuli. Stressful stimuli can be mental, physiological, anatomical or physicalRippetoe-Kilgore, Mark and Lon. 2006. Practical Programming for Strength Training. ISBN 0-9768-0540-5 reactions. The term \'stress\' in this context was coined by Austro-Canadian endocrinologist Hans Selye, who defined the General Adaptation Syndrome or GAS paradigm in 1936.
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The difference between experiences which result in eustress or distress is determined by the disparity between an experience (real or imagined), personal expectations and resources to cope with the stress. A person living in a fashion consistent with personally-accepted expectations may have no stress even if the conditions might be interpreted as adverse from some outside perspective — rural people may live in comparative poverty, and yet be unstressed if their resources are sufficient to meet their needs and expectations. If there is chronic disparity between experience and expectations, stress may be relieved by adjustment of expectations to meet the ongoing experiences or conditions. Alarming experiences, either real or imagined, can trigger a stress response.Ron de Kloet, E; Joels M. & Holsboer F. (2005). "Stress and the brain: from adaptation to disease". Nature Reviews Neuroscience 6 (6): 463-475. PMID 15891777.
Responses to stress include adaptation, psychological coping such as stress management, anxiety, and depression. Over the long term, distress can lead to diminished health or illness; to avoid this, stress must be managed.
This is a model on stress, researched mainly by Hans SelyeSelye, Hans (1950). "Diseases of adaptation". Wisconsin medical journal 49 (6). on rats and other animals. His research involved exposing animals to unpleasant or harmful stimuli such as injections, extreme cold and even vivisection.
He found that all animals showed a very similar series of reactions, broken into three stages. He describes this universal response to the stressors as the General Adaptation Syndrome or GAS in 1956.Seyle, Hans (1956). "A syndrome produced by diverse nocuous agents". Nature.
When the threat or stressor is identified or realised, the body\'s stress response is a state of alarm. During this stage adrenaline will be produced in order to bring about the fight-or-flight response. There is also some activation of the HPA axis, producing cortisol.
If the stressor persists, it becomes necessary to attempt some means of coping with the stress. Although the body begins to try to adapt to the strains or demands of the environment, the body cannot keep this up indefinitely, so its resources are gradually depleted.
In the final stage in the GAS model, all the body\'s resources are eventually depleted and the body is unable to maintain normal function. At this point the initial autonomic nervous system symptoms may reappear (sweating, raised heart rate etc.). If stage three is extended, long term damage may result as the capacity of glands, especially the adrenal gland, and the immune system is exhausted and function is impaired resulting in decompensation. The result can manifest itself in obvious illnesses such as ulcers, depression or even cardiovascular problems, along with other mental illnesses.
The neurochemistry of the general adaptation syndrome is now believed to be well understood, although much remains to be discovered about how this system interacts with others in the brain and elsewhere in the body.
The body reacts to stress first by releasing the catecholamine hormones, epinephrine and norepinephrine, and the glucocorticoid hormones, cortisol and cortisone.
Stress activates the sympathetic branch of the autonomous nervous system and produces the fight-or-flight response, causing the body to divert bloodflow to large muscles as the body prepares to run away from or fight something. Less blood flows to the digestive system and other organs that do not assist in fleeing or fighting, producing dry mouth, motor agitation, sweating, pallor, enlarged pupils and over the long term, insomnia. Modern stressors can cause continual sympathetic nervous system activation with very little opportunity for the parasympathetic nervous system to activate. When the parasympathetic system is active, the bowel and other non-muscle organs receive good blood-flow, the pupils constrict, and the glands all function well and secrete their various compounds. Absence of the autonomic parasympathetic activation leads to poor digestion and may lead to poor healing and organ function.[citation needed]
The hypothalamic-pituitary-adrenal axis (HPA) is a major part of the neuroendocrine system, involving the interactions of the hypothalamus, the pituitary gland, and the adrenal glands. The HPA axis is believed to play a primary role in the body\'s reactions to stress by balancing hormone releases from the adrenaline-producing adrenal medulla, and from the corticosteroid-producing adrenal cortex. Stress can significantly affect many of the body\'s immune systems, as can an individual\'s perceptions of, and reactions to, stress. The term psychoneuroimmunology is used to describe the interactions between the mental state, nervous and immune systems, as well as research on the interconnections of these systems.
It was gradually realized that such concepts as anxiety, antagonism, exhaustion, frustration, distress, despair, overwork, pre-menstrual tension, over-focusing, confusion, mourning, and fear could all come together in a general broad term, stress. The popular use of the term in modern folklore expanded rapidly and created an industry of popular psychology, self-help, psychotherapy, and sometimes quackery. There were a series of films in the 1930s, 1940s, & 1950s that dealt with mad scientists playing with hormones that seem related to this folklore.
The use of the term stress in serious and recognized cases, such as those of post-traumatic stress disorder and psychosomatic illness, has scarcely helped clear analysis of the generalized "stress" phenomenon. Nonetheless, some varieties of stress from negative life events (distress) and from positive life events (eustress) can clearly have a serious physical impact distinct from the troubles of what psychotherapists call the "worried well."
In a review of the scientific literature on the relationship between stress and 4 well-known diseases, the authors found that stress plays a role in triggering or worsening depression and cardiovascular disease and in speeding the progression of HIV/AIDS, and commented that additional studies across a broader range of cancers are needed before fairly evaluating the role of stress in cancer".Cohen S, Janicki-Deverts D, Miller GE (2007). "Psychological stress and disease.". JAMA 298 (14): 1685-7. PMID 17925521. "Stress Contributes To Range Of Chronic Diseases, Review Shows" ScienceDaily.com (Oct. 10, 2007) [1]
Burnout is the emotional exhaustion in the work arena associated with chronic dis-stress leading to a depletion of resources, emotional and mental fatigue. Burnout can be alleviated or averted through the use of stress management.[citation needed] Eustress, by definition, can not lead to burnout.
Burnout itself has been linked to the development of diabetes, with a prospective study of 677 employed men and women finding that after a 3 to 5 year follow up, burnout resulted in a 1.84-fold increased risk of diabetes even after adjusting for confounding factors, and 4.32-fold increase in a subsample of 507 workers after additional control for blood pressure levels.Melamed S, Shirom A, Toker S, Shapira I (2006). "Burnout and risk of type 2 diabetes: a prospective study of apparently healthy employed persons.". Psychosom Med 68 (6): 863-9. PMID 17132837.
Both negative and positive stressors can lead to stress. Some common categories and examples of stressors include:
One evaluation of the different stresses in people\'s lives is the Holmes and Rahe stress scale.
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